Insider Tracker SEC Form 4 insider trades
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SYRE

Spyre Therapeutics, Inc.

Healthcare Pharmaceutical Preparations Market cap: $7.5B Quote and statistics → Sign in to watch SYRE Sign in to set a price alert

Stock Price & Insider Activity

Historical close with open-market insider transaction markers

Insider activity

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Bought$4.0M43 buy days
Sold$445.5M44 sell days
Net insider flow$-441.5Mnet selling · 10 years
Latest trade2026-10-01King-Jones Heidy
Insider trades for this stock
Date Side Insider Role Shares Avg price Value Trades
2026-10-01 Sell King-Jones Heidy Other officer 28,933 $91.03 $2.6M 5
2026-10-01 Sell Turtle Cameron CEO 15,000 $92.01 $1.4M 6
2026-10-01 Sell Burrows Scott L CFO 7,500 $91.83 $688.8K 5
2026-09-30 Sell Burrows Scott L CFO 17,500 $89.89 $1.6M 1
2026-09-02 Sell Burrows Scott L CFO 18,232 $89.35 $1.6M 1
2026-09-02 Sell King-Jones Heidy Other officer 400 $90.00 $36.0K 1
2026-09-01 Sell King-Jones Heidy Other officer 27,999 $87.31 $2.4M 4
2026-09-01 Sell Turtle Cameron CEO 15,000 $87.29 $1.3M 4
2026-09-01 Sell Burrows Scott L CFO 7,500 $87.31 $654.8K 4
2026-08-07 Sell Albers Jeffrey W. Director 23,000 $104.53 $2.4M 3
2026-08-03 Sell Turtle Cameron CEO 15,000 $95.51 $1.4M 5
2026-08-03 Sell Burrows Scott L CFO 7,500 $95.57 $716.8K 3
2026-07-01 Sell Turtle Cameron CEO 15,000 $87.69 $1.3M 3
2026-07-01 Sell Sloan Sheldon Other C-suite 8,334 $87.70 $730.9K 2
2026-07-01 Sell Burrows Scott L CFO 7,500 $87.74 $658.0K 2
2026-06-25 Sell Burrows Scott L CFO 15,000 $87.13 $1.3M 2
2026-06-23 Sell Harwin Peter Evan Director 4,684,781 $85.31 $399.7M 1
2026-06-22 Sell HENDERSON MICHAEL THOMAS Director 20,000 $100.00 $2.0M 1
2026-06-03 Sell Sloan Sheldon Other C-suite 8,333 $75.00 $625.0K 1
2026-06-01 Sell Turtle Cameron CEO 15,000 $70.43 $1.1M 3
2026-06-01 Sell Burrows Scott L CFO 7,500 $71.06 $532.9K 3
2026-05-08 Sell HENDERSON MICHAEL THOMAS Director 80,000 $74.40 $6.0M 4
2026-05-01 Sell Sloan Sheldon Other C-suite 78,333 $71.50 $5.6M 7
2026-05-01 Sell Turtle Cameron CEO 15,000 $71.37 $1.1M 6
2026-05-01 Sell Burrows Scott L CFO 12,500 $71.37 $892.1K 1
2026-04-01 Sell Turtle Cameron CEO 15,000 $49.33 $739.9K 2
2026-04-01 Sell Sloan Sheldon Other C-suite 7,958 $50.00 $397.9K 1
2026-04-01 Sell Burrows Scott L CFO 7,500 $49.34 $370.1K 2
2026-03-03 Sell Burrows Scott L CFO 2,500 $40.65 $101.6K 2
2026-03-02 Sell Turtle Cameron CEO 15,000 $42.19 $632.9K 2
2026-02-02 Sell Turtle Cameron CEO 15,000 $32.80 $492.0K 2
2026-01-02 Sell Turtle Cameron CEO 15,000 $30.68 $460.1K 3
2025-12-01 Sell Turtle Cameron CEO 15,000 $29.02 $435.4K 2
2025-11-03 Sell Turtle Cameron CEO 45,000 $23.33 $1.0M 2
2025-09-02 Sell Burrows Scott L CFO 18,428 $16.26 $299.6K 1
2024-11-06 Sell Albers Jeffrey W. Director 6,700 $36.76 $246.3K 1
2024-10-25 Sell Albers Jeffrey W. Director 300 $36.43 $10.9K 1
2024-09-03 Sell Burrows Scott L CFO 18,531 $28.17 $522.0K 1
2022-08-25 Buy Souza Marcio Director 90,000 $0.56 $50.4K 1
2022-06-08 Buy Hanley Jr. Michael Conick Other C-suite 28,200 $0.71 $20.0K 1
2022-03-16 Buy Quinn Anthony G. CEO 80,079 $2.34 $187.4K 1
2022-03-15 Buy Quinn Anthony G. CEO 42,417 $1.86 $78.9K 1
2022-03-14 Buy Quinn Anthony G. CEO 67,472 $1.93 $130.2K 1
2022-03-11 Buy Alspaugh Jonathan CFO 75,000 $2.08 $156.0K 1
2022-03-11 Buy Quinn Anthony G. CEO 34,777 $2.06 $71.6K 1
2021-12-13 Buy Shanafelt Armen Director 14,685 $3.65 $53.6K 1
2021-12-10 Buy Shanafelt Armen Director 13,516 $3.65 $49.3K 1
2021-12-10 Buy Quinn Anthony G. CEO 10,526 $3.75 $39.5K 1
2021-12-09 Buy Shanafelt Armen Director 121,799 $3.67 $447.0K 1
2021-12-09 Buy Alspaugh Jonathan CFO 50,000 $3.72 $186.0K 1
2021-12-09 Buy Quinn Anthony G. CEO 43,108 $3.70 $159.5K 1
2021-08-18 Buy Alspaugh Jonathan CFO 7,200 $6.72 $48.4K 1
2021-08-17 Buy Alspaugh Jonathan CFO 23,392 $6.50 $152.0K 1
2021-08-16 Buy Alspaugh Jonathan CFO 9,780 $6.37 $62.3K 1
2020-04-30 Buy Quinn Anthony G. CEO 165,000 $4.75 $783.8K 1
2019-06-14 Buy Quinn Anthony G. CEO 5,282 $6.23 $32.9K 1
2019-06-13 Buy Quinn Anthony G. CEO 14,406 $6.17 $88.9K 1
2019-06-12 Buy Quinn Anthony G. CEO 12,217 $6.11 $74.6K 1
2019-05-22 Buy Quinn Anthony G. CEO 3,809 $6.86 $26.1K 1
2019-05-21 Buy Quinn Anthony G. CEO 13,794 $6.89 $95.0K 1
2019-05-20 Buy Quinn Anthony G. CEO 8,989 $6.56 $59.0K 1
2019-05-17 Buy Quinn Anthony G. CEO 6,218 $6.65 $41.3K 1
2019-05-16 Buy Quinn Anthony G. CEO 5,520 $6.83 $37.7K 1
2019-05-15 Buy Quinn Anthony G. CEO 6,256 $6.76 $42.3K 1
2019-02-15 Buy Quinn Anthony G. CEO 719 $7.10 $5.1K 1
2018-09-27 Sell Schuchart Aaron Other C-suite 6,000 $9.50 $57.0K 2
2018-08-15 Buy Quinn Anthony G. CEO 994 $9.13 $9.1K 1
2018-05-11 Sell NOVARTIS AG 10% owner 19,550 $10.06 $196.7K 1
2018-05-10 Sell NOVARTIS AG 10% owner 22,725 $10.13 $230.2K 1
2018-05-09 Sell NOVARTIS AG 10% owner 51,230 $10.11 $517.9K 1
2018-05-08 Sell NOVARTIS AG 10% owner 26,557 $10.03 $266.4K 1
2018-05-07 Sell NOVARTIS AG 10% owner 15,548 $10.11 $157.2K 1
2018-02-15 Buy Quinn Anthony G. CEO 2,000 $6.02 $12.0K 1
2017-12-08 Buy Quinn Anthony G. CEO 600 $5.07 $3.0K 1
2017-12-07 Buy Quinn Anthony G. CEO 2,800 $4.99 $14.0K 1
2017-12-06 Buy Quinn Anthony G. CEO 4,888 $4.92 $24.0K 1
2017-12-05 Buy York Charles N II CFO 10,241 $4.76 $48.7K 1
2017-12-05 Buy Quinn Anthony G. Director 5,065 $4.93 $25.0K 1
2017-12-04 Buy Quinn Anthony G. Director 7,956 $4.98 $39.6K 1
2017-12-04 Buy York Charles N II CFO 3,259 $4.97 $16.2K 1
2017-12-01 Buy York Charles N II CFO 6,500 $4.59 $29.8K 1
2017-12-01 Buy Quinn Anthony G. Director 4,100 $4.53 $18.6K 1
2017-08-15 Buy York Charles N II CFO 1,959 $2.52 $4.9K 1
2017-02-21 Buy ISALY SAMUEL D 10% owner 7,000 $5.36 $37.5K 1
2017-02-17 Buy ISALY SAMUEL D 10% owner 71,800 $5.19 $372.6K 1
2017-02-16 Buy ISALY SAMUEL D 10% owner 30,500 $5.04 $153.7K 1
2017-02-15 Buy York Charles N II CFO 2,000 $4.28 $8.6K 1